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Rabies
Found on all continents, except Antarctica. It causes ~70,000 deaths globally each year and is nearly 100% fatal once symptoms appear.
Rabies is a rare but fatal disease caused by a virus that is transmitted to humans from infected animals, usually through a bite or scratch.
The rabies virus attacks the central nervous system and is almost always fatal once symptoms appear.
Each year, this vaccine-preventable disease is responsible for approximately 59,000 deaths globally. That’s approximately one person dying from rabies every 9 minutes.
Duration: 5 days to 2 years
Virus begins travelling towards the ne
Duration: 0-10 days
What may occur
Symptoms may also include:
loss of appetite, general discomfort, loss of energy
Duration: 2-7 days
hyperventilation, low blood oxygen, loss of speech, lack of coordination, hallucinations, anxiety, depression, paralysis, throat spasms
Duration: 5-14 days
pituitary dysfunction
Untreated rabies is almost always fatal, but 100% vaccine-preventable.
Certain groups of people face higher exposure to rabies due to their environment, profession, or lifestyle. These include:
Children in endemic regions – more likely to interact with animals and less likely to report bites.
Travellers – especially those visiting rural or high-risk areas in Asia and Africa.
Veterinarians and animal handlers – frequent contact with potentially infected animals.
Laboratory staff – those working with rabies virus or related samples.
Communities with limited access to healthcare – where vaccines and post-exposure treatment may not be readily available.
Rabies is almost always fatal once symptoms appear — but it is 100% preventable with the right measures.
Key prevention strategies include:
Vaccination
Pre-exposure vaccination: Recommended for travellers, veterinarians, animal handlers, and people in high-risk areas.
Post-exposure vaccination: Critical after a potential rabies exposure, such as an animal bite or scratch.
Avoid Contact with Stray Animals
Do not approach or handle stray dogs, cats, or wild animals, especially in endemic regions.
Immediate Wound Care
Wash animal bites or scratches thoroughly with soap and water for at least 15 minutes, then seek medical attention immediately.
Awareness and Education
Public health campaigns, responsible pet ownership, and dog vaccination programmes are essential to reducing rabies worldwide.
Once clinical symptoms of rabies appear, the disease is almost always fatal. This makes rapid treatment after exposure absolutely critical.
Post-Exposure Prophylaxis (PEP)If a person is bitten, scratched, or licked on broken skin by a potentially rabid animal, they must seek medical care immediately. Treatment typically includes:
Wound Cleaning
Immediate and thorough washing of the wound with soap and water for at least 15 minutes.
Rabies Vaccination
A series of rabies vaccine doses given over several weeks to trigger the body’s immune response.
Rabies Immunoglobulin (RIG)
Administered in severe cases, particularly when the person has not been previously vaccinated, to provide immediate antibodies against the virus.
No vaccines found for this disease.
02/09/2025
31/07/2025
30/07/2025
02/07/2025
Find out more
01 September 2025
Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard . Adverse events should also be reported to Bavarian Nordic: drug.safety@bavarian-nordic.com.
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